Last edited by Faum
Saturday, August 8, 2020 | History

5 edition of Cell Culture Methods for in vitro Toxicology found in the catalog.

Cell Culture Methods for in vitro Toxicology

  • 367 Want to read
  • 24 Currently reading

Published by Springer .
Written in English

    Subjects:
  • Medical toxicology,
  • Research,
  • Cell Culture,
  • Medical / Nursing,
  • Medical,
  • Toxicology,
  • Life Sciences - Cytology,
  • Medical / Pharmacology,
  • Medical / Toxicology,
  • Medical : Research,
  • Science : Life Sciences - Cytology

  • Edition Notes

    ContributionsG. Stacey (Editor), Alan Doyle (Editor), Margherita Ferro (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages168
    ID Numbers
    Open LibraryOL8369945M
    ISBN 101402004273
    ISBN 109781402004278

    In vitro methods in toxicology. [C K Atterwill; C E Steele;] Application of thyroid cell culture to the study of thyrotoxicity C. G. Brown; 7. In vitro methods to investigate toxic lung disease A. Poole and R. C. Brown; 8. Metabolism and toxicity of drugs in mammalian hepatocyte culture R. J. Chenery; 9. In vitro evaluation of haemic. In Vitro Methods in Toxicology by C.K. Atterwill, , available at Book Depository with free delivery worldwide.

      4 In Vitro Methods for Predicting In Vivo Toxicity In vitro toxicology Tissue culture Primary cell cultures Established cell lines Acute toxicity in vitro Cytotoxicity testing Choice of cell line Liver Skin Eye Repeated dose toxicity Author: Lesley Stanley. The American embryologist Ross Granville Harrison (–) developed the first techniques of cell culture in vitro in the first decade of the twentieth century [ 52 – 56 ]. In Harrison's experiments (–, at the Yale University), small pieces of living frog embryonic tissue were isolated and grew outside the body. He placed the Cited by: 6.

    Viruses, which only replicate in living cells, are studied in the laboratory in cell or tissue culture, and many animal virologists refer to such work as being in vitro to distinguish it from in vivo work in whole animals. Polymerase chain reaction is a method for selective replication of . Application of thyroid cell culture to the study of thyrotoxicity C. G. Brown; 7. In vitro methods to investigate toxic lung disease A. Poole and R. C. Brown; 8. Metabolism and toxicity of drugs in mammalian hepatocyte culture R. J. Chenery; 9. In vitro evaluation of haemic systems in toxicology J. S. H. Luke and G. R. Betton; Part II.


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Cell Culture Methods for in vitro Toxicology Download PDF EPUB FB2

Buy Cell Culture Methods for In Vitro Toxicology on FREE SHIPPING on qualified orders Cell Culture Methods for In Vitro Toxicology: G. Stacey, Alan Doyle, Margherita Ferro: : Books. Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies.

It deals with major Cell Culture Methods for in vitro Toxicology book types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models.

Cell Culture Methods for In Vitro Toxicology - Kindle edition by Stacey, G., Doyle, Alan, Ferro, Margherita. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Cell Culture Methods for In Vitro Toxicology.

Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types.

Summary: Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. Optimization of cell culture is the major primary step to in vitro studies as it includes handling of cells and tissues outside the body under controlled conditions.

Explant, organotype culture, primary, secondary cell lines, and three-dimensional culture methods are routinely used for in vitro screening of toxicants.

In Vitro Methods in Toxicology. First published inthis book describes tissue (cell and organ) culture techniques which could be used at a critical predevelopment stage to screen for drug-inducing toxicity or to analyse the molecular mechanisms of toxicity at a. Abstract. Compared to other biomedical disciplines, cell culture systems have only recently been systematically adopted for use in toxicology (Paganuzzi Stammati et al.

), due, in particular, to the difficulty in extrapolating in vitro data to the in vivo situation for regulatory by: Good Cell Culture Practices (GCCP) is of high relevance to in vitro toxicology. The European Society of Toxicology In Vitro (ESTIV), the Center for Alternatives for Animal Testing (CAAT) and the.

Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies.

It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating toin vitrocell models.

Bondesson, Inger Ekwall, Björn Hellberg, Sven Romert, Lennart Stenberg, Kjell and Walum, Erik MEIC—A new international multicenter project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests.

Cell Biology and Toxicology, Vol. 5, Issue. 3, p. Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies.

It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge Brand: Springer Netherlands. First Published inIntroduction to In Vitro Cytotoxicology examines in vitro cytotoxicology, which offers new methodologies to toxicity testing.

This important new discipline of modern toxicology is gaining increased acceptance as a viable alternative to traditional testing methods.

The text d. In Vitro Methods in Pharmaceutical Research provides a comprehensive guide to laboratory techniques for evaluating in vitro organ toxicity using cellular models. Step-by-step practical tips on how to perform and interpret assays for drug metabolism and toxicity assessment are provided, along with a comparison of different techniques available.

Toxicity Tests with Mammalian Cell Cultures B. EKWALL, V. SILANO, A. PAGANUZZI-STAMMATI AND F. ZUCCO INTRODUCTION Cell culture can be used to screen for toxicity both by estimation of the basal functions of the cell (i.e.

those processes common to all types of cells) or by tests on specialized cell functions (Ekwall, b).File Size: 8MB. Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies.

It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Section III introduces and discusses in vitro alternatives to animal toxicology tests.

This section emphasizes cell culture methodology and cellular methods for acute systemic toxicity, target organ toxicity, and local toxicity. The contributors present the advantages and disadvantages of alternative methods.

Methods in Toxicology, Volume 1: In Vitro Biological Systems, Part A provides basic techniques employed by widely recognized scientists to prepare and maintain the biological components of in vitro model systems.

Gastric Mucosal Cell Culture for Toxicological Study Small Intestinal Enterocytes Maintenance and Characterization of an Book Edition: 1. and for growing cells in 3D cell culture, two areas of growing importance to cell culture research, have been added to this latest edition of the handbook. The handbook is intended as a guide rather than an in-depth text book of cell culture and you are encouraged to consult relevant specialised literature to obtain more detailed Size: 2MB.

Cytotechnology is an international journal covering up-to-date developments, methods and techniques in cell culture research involving in vitro systems, as well as the applications of that research in human and veterinary medicine and animal cell biotechnology.

D.W. Straughan, J.H. Fentem, and M. Balls, Replacement Alternative and Complementary In Vitro Methods in Pharamaceutical Research. M.D. Barratt and M. Chamberlain, Integration of QSAR and In Vitro Toxicology. F.A. Barile, Continuous Cell Lines as a Model for Drug Toxicity Assessment. P. Bach, In Vitro Models for Nephrotoxicity Studies.

A.E.M. Vickers, Experimental In Vitro Models to Book Edition: 1.In vitro toxicity testing is the scientific analysis of the effects of toxic chemical substances on cultured bacteria or mammalian cells.

In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as.Indeed, if good cell culture principles are critical to take into consideration for all uses of in vitro test methods for toxicity testing, the level of application of such principles may depend on the stage of development of the test method as well as on the applications of the test methods, i.e., academic innovative research vs.

regulatory Cited by: 8.